When a price reaches the target, I take money off the table. At least 50% of my position is sold. The other I let run. I generally trail the 14 DMA.
I want to stay on the trend as long as possible. I know I will never catch the exact top. Following the 14 DMA is a good way to ensure I keep locking in profits and catch most of the trend. Horizontal breakouts into all time highs are the most profitable trades I make.